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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFC1 All Species: 10
Human Site: S1126 Identified Species: 20
UniProt: P35251 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35251 NP_002904.3 1148 128255 S1126 M I K K K T K S S K P S K P E
Chimpanzee Pan troglodytes XP_001140765 1148 128250 S1126 M I K K K T K S S K P S K P E
Rhesus Macaque Macaca mulatta XP_001091287 1148 128475 P1126 M I K K K T K P S K P S K P E
Dog Lupus familis XP_536259 1145 128125 S1123 M I K K K T K S S K P S K S E
Cat Felis silvestris
Mouse Mus musculus P35601 1131 125967 S1110 I K K K T R S S K P S K S E R
Rat Rattus norvegicus NP_445999 1131 125770 R1108 M I K Q K K T R S S K P S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512744 1233 136122 K1206 E T D A M I K K K T K S S K P
Chicken Gallus gallus NP_001006456 1147 128454 K1121 M I K Q K K G K S S K L P K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35600 986 108596 A965 K R T T T S K A S G G S K K A
Honey Bee Apis mellifera XP_397246 911 103001 E890 K N T E S K S E K K G K K N S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797949 906 99249 A885 G S K G K A P A K G K A P V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38630 861 94885 K840 K L I K Q K A K P T K R K T A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 89.3 N.A. 82.4 81.3 N.A. 67.4 68.9 N.A. N.A. N.A. 39.9 36.2 N.A. 38
Protein Similarity: 100 99.6 98.5 93.7 N.A. 89.5 88.5 N.A. 77.2 79.6 N.A. N.A. N.A. 55.9 53.6 N.A. 52.2
P-Site Identity: 100 100 93.3 93.3 N.A. 20 33.3 N.A. 13.3 33.3 N.A. N.A. N.A. 26.6 13.3 N.A. 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 26.6 40 N.A. 13.3 40 N.A. N.A. N.A. 40 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 9 17 0 0 0 9 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 9 0 0 0 9 0 0 0 0 0 9 34 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 9 0 0 9 0 0 17 17 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 50 9 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 25 9 67 50 59 34 50 25 34 42 42 17 59 34 9 % K
% Leu: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % L
% Met: 50 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 9 9 9 9 34 9 17 25 9 % P
% Gln: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 0 0 9 0 9 0 0 0 9 0 0 17 % R
% Ser: 0 9 0 0 9 9 17 34 59 17 9 50 25 9 17 % S
% Thr: 0 9 17 9 17 34 9 0 0 17 0 0 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _